SCHEMBL548041

SCHEMBL548041

Cc1ccc(C(=O)C=Cc2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
MAOB P27338 5/20 1.00
MAOA P21397 4/20 1.00
RAB9A P51151 4/20 1.00
POLB P06746 1/20 1.00
F3 P13726 3/20 0.82
CYP3A4 P08684 3/20 0.72
ALDH1A1 P00352 3/20 0.72
CYP1B1 Q16678 2/20 0.72
HPGD P15428 1/20 0.72
ESR1 P03372 1/20 0.70
ESR2 Q92731 1/20 0.70
CXCL12 P48061 1/20 0.70
KMT2A Q03164 4/20 0.69
MEN1 O00255 3/20 0.69
HSPD1 P10809 2/20 0.69
HSPE1 P61604 2/20 0.69
PKM P14618 1/20 0.69
NFKB1 P19838 1/20 0.69
NFKB2 Q00653 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965062 1.00 MAPT (1.00) MAPTMAOBMAOARAB9APOLB
SCHEMBL548040 1.00 MAPT (1.00) MAPTMAOBMAOARAB9APOLB
SCHEMBL8965069 1.00 MAPT (1.00) MAPTMAOBMAOARAB9APOLB
4,4'-Dimethylchalcone SCHEMBL979560 0.93 MAPT (1.00) MAPTMAOBMAOARAB9APOLB
4,4'-Dimethylchalcone SCHEMBL979559 0.93 MAPT (1.00) MAPTMAOBMAOARAB9APOLB
SCHEMBL25236411 0.91 F3 (1.00) MAPTMAOBMAOARAB9APOLB
SCHEMBL25223420 0.91 F3 (1.00) MAPTMAOBMAOARAB9APOLB
SCHEMBL25211913 0.91 F3 (1.00) MAPTMAOBMAOARAB9APOLB
4,4'-Dihydroxychalcone SCHEMBL773588 0.91 F3 (1.00) MAPTMAOBMAOARAB9APOLB
4,4'-Dihydroxychalcone SCHEMBL25202156 0.91 F3 (1.00) MAPTMAOBMAOARAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP claimed
US-5110706-A Photoresists for highly reflective substrates JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-05-05 US claimed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2025084342-A1 IODINE-CONTAINING (METH)ACRYLATE COMPOUND, IODINE-CONTAINING (METH)ACRYLATE (CO)POLYMER, LITHOGRAPHY COMPOSITION, RESIST COMPOSITION, UNDERLAYER-FILM-FORMING COMPOSITION, AND METHOD FOR PRODUCING IODINE-CONTAINING (METH)ACRYLATE COMPOUND 三菱瓦斯化学株式会社 2025-04-24 WO disclosed
WO-2025084340-A1 IODINE-CONTAINING (METH)ACRYLATE COMPOUND, IODINE-CONTAINING (METH)ACRYLATE (CO)POLYMER, LITHOGRAPHY COMPOSITION, RESIST COMPOSITION, BOTTOM LAYER-FORMING COMPOSITION, AND METHOD FOR PRODUCING IODINE-CONTAINING (METH)ACRYLATE COMPOUND 三菱瓦斯化学株式会社 2025-04-24 WO disclosed
WO-2025084341-A1 IODINE-CONTAINING (METH)ACRYLATE COMPOUND, IODINE-CONTAINING (METH)ACRYLATE (CO)POLYMER, LITHOGRAPHY COMPOSITION, RESIST COMPOSITION, UNDERLAYER FILM-FORMING COMPOSITION, AND METHOD FOR PRODUCING IODINE-CONTAINING (METH)ACRYLATE COMPOUND 三菱瓦斯化学株式会社 2025-04-24 WO disclosed
WO-2025079631-A1 COMPOSITION, RESIN COMPOSITION, COMPOSITION FOR FILM FORMATION, COMPOSITION FOR FORMING LITHOGRAPHIC FILM, AND COMPOSITION FOR FORMING RESIST FILM 三菱瓦斯化学株式会社 2025-04-17 WO disclosed
WO-2025079648-A1 COMPOUND, COMPOSITION, RESIN COMPOSITION, COMPOSITION FOR FORMING FILM, COMPOSITION FOR FORMING FILM FOR LITHOGRAPHY, AND COMPOSITION FOR FORMING RESIST FILM 三菱瓦斯化学株式会社 2025-04-17 WO disclosed
WO-2025033019-A1 COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND PRODUCTION METHOD 三菱瓦斯化学株式会社 2025-02-13 WO disclosed
US-5952150-A COMPRISING A DISULFONYLMETHANE DERIVATIVE, A RESIN PROTECTED BY AN ACID DECOMPOSABLE GROUP OR AN ALKALI-SOLUBLE RESIN AND AN ALKALI SOLUBILITY CONTROL AGENT; PHOTORESISTS JSR CORPORATION (JP) 1999-09-14 US disclosed
EP-0898201-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-02-24 EP disclosed
EP-0819981-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-01-21 EP disclosed
EP-0660187-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1997-03-05 EP disclosed
US-5556734-A RESISTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-09-17 US disclosed
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP disclosed
EP-0660187-A1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-06-28 EP disclosed
US-5110706-A Photoresists for highly reflective substrates JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-05-05 US disclosed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAOB 1004/4885MAOA 1902/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOB 2435/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.