Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048674 | 0.91 | ALOX5 (0.71) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL8965207 | 0.88 | ACACB (0.48) | ALOX5EPHX2ACACB | |
| SCHEMBL8305355 | 0.86 | ALOX5 (0.58) | ALOX5EPHX2 | |
| SCHEMBL9048203 | 0.85 | ALOX5 (0.79) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9046903 | 0.84 | ALOX5 (0.74) | ALOX5EPHX2 | |
| SCHEMBL9047292 | 0.83 | ALOX5 (0.64) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9048949 | 0.82 | ALOX5 (0.62) | ALOX5EPHX2 | |
| SCHEMBL9046357 | 0.82 | ALOX5 (0.65) | ALOX5EPHX2 | |
| SCHEMBL9049196 | 0.82 | ALOX5 (0.62) | ALOX5EPHX2 | |
| SCHEMBL9048434 | 0.82 | ALOX5 (0.62) | ALOX5EPHX2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | claimed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |
| EP-0561882-B1 | HYDROXAMIC ACID DERIVATIVES WHICH INHIBIT LIPOXYGENASE | PFIZER (US) | 1994-08-31 | — | — | EP | disclosed |