Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965068 | 0.88 | ALOX5 (0.61) | ACACBALOX5EPHX2 | |
| SCHEMBL8966035 | 0.79 | ALOX5 (0.57) | ALOX5EPHX2 | |
| SCHEMBL9048674 | 0.78 | ALOX5 (0.71) | ACACBALOX5EPHX2 | |
| SCHEMBL9048409 | 0.75 | ALOX5 (0.53) | ACACBALOX5EPHX2FFAR1 | |
| SCHEMBL9348018 | 0.75 | ALOX5 (0.81) | ACACBALOX5PTGS2EPHX2 | |
| SCHEMBL30153463 | 0.74 | CYP1A2 (0.59) | ACACBCYP1A1CYP1A2CYP1B1PTGS2 | |
| SCHEMBL8305355 | 0.74 | ALOX5 (0.58) | ALOX5EPHX2 | |
| SCHEMBL9707327 | 0.73 | ALOX5 (0.56) | ALOX5PTGS2 | |
| SCHEMBL9195413 | 0.73 | FFAR1 (0.54) | ALOX5FFAR1 | |
| SCHEMBL9048203 | 0.73 | ALOX5 (0.79) | ACACBALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | claimed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |
| EP-0696271-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025430-A1 | CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING HYDROXAMIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |