Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965728 | 0.84 | PTGDR2 (0.57) | PTGDR2PTGDRPTGIRPPARGPPARA | |
| SCHEMBL8354768 | 0.82 | PTGDR2 (0.53) | PTGDR2PTGDRPTGIR | |
| SCHEMBL8965035 | 0.81 | PTGDR2 (0.55) | PTGDR2PTGDRPTGIRPPARGPPARA | |
| SCHEMBL8804127 | 0.79 | PTGDR2 (0.67) | PTGDR2PTGDRPTGIRPPARGPPARA | |
| SCHEMBL8358402 | 0.78 | PTGDR2 (0.55) | PTGDR2PTGDRPTGIRPPARGPPARA | |
| SCHEMBL8965375 | 0.76 | PTGDR2 (0.63) | PTGDR2PTGDRPTGIRPPARGPPARA | |
| SCHEMBL3168945 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGDRPPARGPPARDPPARA | |
| SCHEMBL3174445 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGDRPPARGPPARDPPARA | |
| SCHEMBL3165304 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGDRPPARGPPARDPPARA | |
| SCHEMBL3166257 | 0.74 | PTGDR2 (0.75) | PTGDR2PTGDRPTGIRPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |