Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.88 |
| ▸ | APP | P05067 | 4/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TOP2A | P11388 | 2/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.64 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965107 | 1.00 | BACE1 (0.88) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL3218761 | 0.94 | BACE1 (1.00) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL3218771 | 0.94 | BACE1 (1.00) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL12402527 | 0.89 | BACE1 (0.72) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL3216545 | 0.88 | APP (0.86) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL3216555 | 0.88 | APP (0.86) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL10077674 | 0.87 | BACE1 (0.72) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL14303722 | 0.87 | BACE1 (0.72) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL3215397 | 0.87 | MAPT (0.80) | BACE1APPAKR1B1MAOBMAPT | |
| SCHEMBL3215412 | 0.87 | MAPT (0.80) | BACE1APPAKR1B1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057995-A2 | Bioactive compound for cosmetic purposes | Evonik Goldschmidt GmbH (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-5525457-A | Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0428398-B1 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5110706-A | Photoresists for highly reflective substrates | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |