Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.86 |
| ▸ | MAPT | P10636 | 9/20 | 0.86 |
| ▸ | BACE1 | P56817 | 6/20 | 0.86 |
| ▸ | MMP9 | P14780 | 4/20 | 0.86 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.86 |
| ▸ | TSHR | P16473 | 2/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.86 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.86 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.86 |
| ▸ | MAOA | P21397 | 2/20 | 0.86 |
| ▸ | MAOB | P27338 | 2/20 | 0.86 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.86 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.86 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.86 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.86 |
| ▸ | STAT3 | P40763 | 2/20 | 0.86 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216555 | 1.00 | APP (0.86) | APPMAPTBACE1MMP9NFKB1 | |
| SCHEMBL3211934 | 0.93 | APP (0.84) | APPMAPTBACE1MMP9NFKB1 | |
| SCHEMBL3211947 | 0.93 | APP (0.84) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8440 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL250984 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8336603 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL17629819 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL2804734 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL6901740 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL17629818 | 0.93 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857639-B2 | Method for treating breast cancer | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-01-02 | — | — | US | disclosed |
| US-20230346833-A1 | POROUS SILICATE AND/OR ALUMINOSILICATE MATRIX/CERIUM OXIDE NANOPARITLE NANOCARRIER FOR COMBINATION ANTI-CANCER THERAPEUTIC AND ANTIOXIDANT DELIVERY | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-11-02 | — | — | US | disclosed |
| US-11793892-B2 | Nanosilica carrier with spions and a curcuminoid | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-10-24 | — | — | US | disclosed |
| US-11779652-B2 | Porous silicate/magnetic ferrite nanocarrier for combination anti-cancer therapeutic and antioxidant delivery | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-10-10 | — | — | US | disclosed |
| US-11738097-B2 | Curcuminoid chemotherapeutic drug carrier composition | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-08-29 | — | — | US | disclosed |
| US-20230190846-A1 | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF IN TREATING MUSCLE ATROPHY | LEE, Tzung-Yan (TW) | 2023-06-22 | — | — | US | disclosed |
| US-20230161247-A1 | ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2023-05-25 | — | — | US | disclosed |
| US-20160022605-A1 | METHODS FOR REDUCING MICROSATELLITE INSTABILITY INDUCED BY CHEMOTHERAPY AND METHODS FOR SCREENING ANTIOXIDANTS THAT SUPPRESS DRUG-INDUCED MICROSATELLITE INSTABILITY WHILE ENHANCING THE CYTOTOXICITY OF CHEMOTHERAPEUTIC AGENTS | CHANG CHRISTINA LING (TW) | 2016-01-28 | — | — | US | disclosed |
| US-20150377894-A1 | Method and System for Measuring the Pharmacokinetics of Liposomal Curcumin and its Metabolite Tetrahydrocurcumin | SIGNPATH PHARMA INC. | 2015-12-31 | — | — | US | disclosed |
| US-9173920-B2 | Methods of treating muscular wasting diseases using NF-KB activation inhibitors | THERALOGICS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20120122913-A1 | COMBINATION OF CURCUMINOIDS AND MTOR INHIBITORS FOR THE TREATMENT OF TAUOPATHIES | INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFQUE | 2012-05-17 | — | — | US | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
| WO-2009066303-A2 | NEW SYNERGISTIC PHYTOCHEMICAL COMPOSITION FOR THE TREATMENT OF OBESITY | GOKARAJU GANGA RAJU (IN) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009017874-A9 | NOVEL CURCUMIN DERIVATIVES AND THEIR PHARMACEUTICAL USES THEREOF | UNIV ROCHESTER (US) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009017874-A2 | NOVEL CURCUMIN DERIVATIVES AND THEIR PHARMACEUTICAL USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2009-02-05 | — | — | WO | disclosed |
| US-5525457-A | Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0428398-B1 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5110706-A | Photoresists for highly reflective substrates | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | APP 2/4885MAPT 8/4885BACE1 1/4885 |
| US-11793892-B2 | Nanosilica carrier with spions and a curcuminoid | TFRC, CALCA, HAMP | APP 1874/4885MAPT 1168/4885BACE1 3215/4885 |
| US-11779652-B2 | Porous silicate/magnetic ferrite nanocarrier for combination anti-cancer therapeutic and antioxidant delivery | SLC40A1, AIFM2, FECH | APP 4234/4885MAPT 1222/4885BACE1 3727/4885 |
| US-20120122913-A1 | COMBINATION OF CURCUMINOIDS AND MTOR INHIBITORS FOR THE TREATMENT OF TAUOPATHIES | MAPT, MTOR, RPTOR | APP 14/4885MAPT 1/4885BACE1 37/4885 |
| US-11738097-B2 | Curcuminoid chemotherapeutic drug carrier composition | TFRC, HAMP, SLC40A1 | APP 2460/4885MAPT 923/4885BACE1 3599/4885 |
| US-20160022605-A1 | METHODS FOR REDUCING MICROSATELLITE INSTABILITY INDUCED BY CHEMOTHERAPY AND METHODS FOR SCREENING ANTIOXIDANTS THAT SUPPRESS DRUG-INDUCED MICROSATELLITE INSTABILITY WHILE ENHANCING THE CYTOTOXICITY OF CHEMOTHERAPEUTIC AGENTS | MSH2, PCNA, PMS2 | APP 4384/4885MAPT 4571/4885BACE1 3669/4885 |
| US-20230190846-A1 | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF IN TREATING MUSCLE ATROPHY | HNRNPU, UTRN, LGMN | APP 3977/4885MAPT 1836/4885BACE1 3505/4885 |
| US-11857639-B2 | Method for treating breast cancer | SLC40A1, AIFM2, FECH | APP 4523/4885MAPT 1581/4885BACE1 3785/4885 |
| US-20230346833-A1 | POROUS SILICATE AND/OR ALUMINOSILICATE MATRIX/CERIUM OXIDE NANOPARITLE NANOCARRIER FOR COMBINATION ANTI-CANCER THERAPEUTIC AND ANTIOXIDANT DELIVERY | CAT, SP1, GPX1 | APP 3667/4885MAPT 868/4885BACE1 3013/4885 |
| US-20150377894-A1 | Method and System for Measuring the Pharmacokinetics of Liposomal Curcumin and its Metabolite Tetrahydrocurcumin | TTPA, PLPBP, HAMP | APP 448/4885MAPT 1564/4885BACE1 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.