SCHEMBL8965151

SCHEMBL8965151

CCn1c2ccccc2c2cc(C(c3ccccc3)c3cc4c5ccccc5n(CC)c4c4ccccc34)c3ccccc3c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
ALDH1A1 P00352 6/20 0.43
MAPT P10636 6/20 0.43
HTT P42858 4/20 0.43
KMT2A Q03164 4/20 0.43
HPGD P15428 3/20 0.43
MEN1 O00255 3/20 0.43
MAPK1 P28482 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
HBB P68871 1/20 0.43
PGR P06401 1/20 0.41
LMNA P02545 4/20 0.41
NSD2 O96028 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
POLB P06746 2/20 0.40
PKM P14618 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540023 0.89 MAPT (0.45) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL3156176 0.75 MAPT (0.58) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL14208786 0.74 ALDH1A1 (0.59) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL10540568 0.74 MAPT (0.57) ALDH1A1MAPTHTTKMT2AMEN1
SCHEMBL10718200 0.72 MAPT (0.55) ALDH1A1MAPTHTTKMT2AMEN1
SCHEMBL9500947 0.70 ALDH1A1 (0.43) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL8990417 0.70 ALDH1A1 (0.50) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL29139893 0.70 ALDH1A1 (0.50) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL19213230 0.70 ALDH1A1 (0.63) KDM4EALDH1A1MAPTHTTKMT2A
SCHEMBL9779179 0.70 KDM4E (0.47) KDM4EALDH1A1MAPTHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0292322-B1 Dyes suitable for sensitization of photoconductive systems MINNESOTA MINING & MFG (US) 1994-02-02 EP claimed
EP-0453278-B1 Liquid electrophotographic toner with acid containing polyester resins MINNESOTA MINING & MFG (US) 1996-08-14 EP disclosed
EP-0467609-B1 Method for repeated electrical charging of a photoconductor layer and corresponding apparatus MINNESOTA MINING & MFG (US) 1996-02-21 EP disclosed
EP-0376460-B1 Liquid electrophotographic toner MINNESOTA MINING & MFG (US) 1995-02-22 EP disclosed
US-5302482-A Liquid electrophotographic toner MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-04-12 US disclosed
EP-0292322-B1 Dyes suitable for sensitization of photoconductive systems MINNESOTA MINING & MFG (US) 1994-02-02 EP disclosed
EP-0498535-A1 Liquid electrophotographic toner MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-12 EP disclosed
EP-0467609-A2 Method for repeated electrical charging of a photoconductor layer and corresponding apparatus MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-22 EP disclosed
US-5083163-A PHOTOCONDUCTOR RESETTING FOLLOWING MULTIPLE CHARGE IMAGES MINNESOTA MINING & MANUFACTURING COMPANY (US) 1992-01-21 US disclosed
EP-0453278-A1 Liquid electrophotographic toner with acid containing polyester resins MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-10-23 EP disclosed
US-4853310-A STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-01 US disclosed
EP-0152411-B1 SILICONE RELEASE COATINGS FOR EFFICIENT TONER TRANSFER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-05-10 EP disclosed
US-4820846-A SENSITIZERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-11 US disclosed
EP-0292322-A2 Dyes suitable for sensitization of photoconductive systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-23 EP disclosed
EP-0102745-B1 TRIARYLMETHANE COMPOUNDS, THEIR PREPARATION AND USE AS PHOTOCONDUCTIVE SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-08 EP disclosed
EP-0194776-A2 Multicolor toner images in electrography MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-17 EP disclosed
US-4600673-A Silicone release coatings for efficient toner transfer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-07-15 US disclosed
EP-0152411-A1 SILICONE RELEASE COATINGS FOR EFFICIENT TONER TRANSFER. MINNESOTA MINING & MFG (US) 1985-08-28 EP disclosed
WO-1985000901-A1 SILICONE RELEASE COATINGS FOR EFFICIENT TONER TRANSFER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-02-28 WO disclosed
EP-0102745-A2 Triarylmethane compounds, their preparation and use as photoconductive systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-03-14 EP disclosed