Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.77 |
| ▸ | CA9 | Q16790 | 15/20 | 0.77 |
| ▸ | CA1 | P00915 | 14/20 | 0.77 |
| ▸ | CA12 | O43570 | 12/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.77 |
| ▸ | CA7 | P43166 | 4/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | CA4 | P22748 | 3/20 | 0.77 |
| ▸ | CA5A | P35218 | 3/20 | 0.77 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.77 |
| ▸ | CA6 | P23280 | 2/20 | 0.77 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL28616095 | 0.88 | CA2 (0.90) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL30659052 | 0.88 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL2798899 | 0.88 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL31544839 | 0.88 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL740 | 0.88 | CA2 (1.00) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL20567505 | 0.86 | CA2 (0.77) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28258818 | 0.86 | CA2 (0.85) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL28201481 | 0.86 | CA2 (0.85) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL27698504 | 0.86 | CA2 (0.85) | CA2CA9CA1CA12CA14 | |
| Sulfanilamide SCHEMBL1155220 | 0.85 | CA2 (0.94) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110216766-B | Method for manufacturing free-form low-density flame-retardant shaving board | 中国林业科学研究院木材工业研究所 | 2021-06-29 | — | — | CN | claimed |
| CN-110216766-B | Method for manufacturing free-form low-density flame-retardant shaving board | 中国林业科学研究院木材工业研究所 | 2021-06-29 | — | — | CN | disclosed |
| EP-0346162-B1 | Water-soluble, film-forming inorganic compounds, fireproof and fire-resistance composites and fire-resistance, flexible, sheet composite covering materials formed by the use of the compounds, and fire-resistance-covering process | KOHMIX CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5368950-A | Alkali metal silica composites | KOHMIX CO., LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5234631-A | From reacting metal, hydrofluoric or boric acid and their salts amd alkali hydroxide | KOHMIX CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| US-5049316-A | Metal, hydrofluoric acid, boric acid, alkali hydroxide | KOHMIX CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0346162-A2 | Water-soluble, film-forming inorganic compounds, fireproof and fire-resistance composites and fire-resistance, flexible, sheet composite covering materials formed by the use of the compounds, and fire-resistance-covering process | KOHMIX CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |