SCHEMBL8965180

SCHEMBL8965180

CCn1c2ccccc2c2cc(OC)c(C(=O)O)cc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.58
MAPT P10636 9/20 0.54
KDM4E B2RXH2 8/20 0.54
HPGD P15428 7/20 0.54
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
LMNA P02545 5/20 0.54
HTT P42858 2/20 0.54
HCRTR1 O43613 2/20 0.54
ALDH1A1 P00352 5/20 0.53
POLB P06746 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
MAPK1 P28482 3/20 0.52
BLM P54132 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ATM Q13315 1/20 0.51
NPSR1 Q6W5P4 3/20 0.50
RAB9A P51151 2/20 0.50
TP53 P04637 1/20 0.49
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8964575 0.81 TP53 (0.52) MAPTKDM4EHPGDMEN1KMT2A
SCHEMBL22166476 0.75 PSEN1 (0.54) PTGER4MAPTKDM4EHPGDMEN1
SCHEMBL8964807 0.75 TP53 (0.49) PTGER4MAPTKDM4EHPGDMEN1
SCHEMBL2734561 0.75 ALDH1A1 (0.78) PTGER4MAPTKDM4EHPGDMEN1
SCHEMBL27722947 0.75 ALDH1A1 (0.65) PTGER4MAPTKDM4EHPGDMEN1
SCHEMBL13979310 0.74 KDM4E (0.70) MAPTKDM4EHPGDMEN1KMT2A
SCHEMBL6764355 0.74 ALDH1A1 (0.56) PTGER4KDM4EHPGDMEN1KMT2A
SCHEMBL6755176 0.74 PTGER4 (0.52) PTGER4MAPTKDM4EHPGDMEN1
SCHEMBL11061794 0.74 ALDH1A1 (0.60) PTGER4MAPTKDM4EHPGDMEN1
SCHEMBL1149968 0.73 MAPT (0.84) MAPTKDM4EHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5587112-A DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) 1996-12-24 US disclosed