Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964575 | 0.79 | TP53 (0.52) | TP53MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL28471451 | 0.77 | SRC (0.51) | TP53MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL13979310 | 0.75 | KDM4E (0.70) | TP53MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL14822412 | 0.75 | RORC (0.77) | MAPTKDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL8965180 | 0.75 | PTGER4 (0.58) | TP53MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL18121158 | 0.74 | KDM4E (0.68) | TP53MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL29643208 | 0.74 | PTGER4 (0.63) | MAPTKDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL21599721 | 0.74 | PTGER4 (0.59) | MAPTKDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL5892136 | 0.74 | PTGER4 (0.63) | MAPTKDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL28809379 | 0.74 | RORC (0.48) | MAPTKDM4EHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587112-A | DETECTION AND MEASUREMENT OF HIGH ENERGY PARTICLES AND ELECTROMAGNETC RADIATION | PHILADELPHIA COLLEGE OF PHARMACY AND SCIENCE (US) | 1996-12-24 | — | — | US | disclosed |