Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965837 | 0.83 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8800278 | 0.83 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8964963 | 0.82 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8965790 | 0.81 | ALOX5 (0.61) | ALOX5HDAC6 | |
| SCHEMBL8965783 | 0.80 | ALOX5 (0.59) | ALOX5HDAC6 | |
| SCHEMBL8799938 | 0.78 | ALOX5 (0.62) | ALOX5HDAC6 | |
| SCHEMBL8965348 | 0.76 | ALOX5 (0.57) | ALOX5HDAC6 | |
| SCHEMBL8965428 | 0.75 | ALOX5 (0.55) | ALOX5HDAC6 | |
| SCHEMBL8803948 | 0.74 | ALOX5 (0.58) | ALOX5HDAC6PDE10A | |
| SCHEMBL8800024 | 0.74 | ALOX5 (0.43) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |