Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965790 | 0.99 | ALOX5 (0.61) | ALOX5EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8964963 | 0.82 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8800278 | 0.81 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8965837 | 0.81 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL9564300 | 0.81 | ALOX5 (0.67) | ALOX5EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8965337 | 0.80 | ALOX5 (0.61) | ALOX5HDAC6 | |
| SCHEMBL8799819 | 0.78 | ALOX5 (0.60) | ALOX5EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8804130 | 0.78 | ALOX5 (0.60) | ALOX5EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8802299 | 0.78 | ALOX5 (0.60) | ALOX5EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8799972 | 0.78 | ALOX5 (0.60) | ALOX5EPHX2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |