Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964833 | 0.79 | POLB (0.33) | TSHRMAPT | |
| SCHEMBL9514196 | 0.78 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL9460546 | 0.75 | MAPK1 (0.40) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL8965318 | 0.69 | ALDH1A1 (0.44) | TSHRMAPK1MEN1MAPTKMT2A | |
| SCHEMBL8965387 | 0.64 | ALDH1A1 (0.42) | TSHRMAPTKMT2A | |
| SCHEMBL3271932 | 0.63 | MEN1 (0.53) | MEN1MAPTKMT2A | |
| SCHEMBL8964648 | 0.63 | PTGDR2 (0.37) | TSHRMAPK1MEN1MAPTKMT2A | |
| SCHEMBL2907656 | 0.63 | — | — | |
| SCHEMBL5277361 | 0.62 | LMNA (0.42) | TSHRMAPK1HTTMAPT | |
| SCHEMBL28521977 | 0.62 | ALDH1A1 (0.30) | NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459244-B1 | Sulphonilised carboxylic acid amides | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0569810-A1 | Sulphonylamide herbicides | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0459244-A1 | Sulphonilised carboxylic acid amides | BAYER AG (DE) | 1991-12-04 | — | — | EP | disclosed |