Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965356 | 0.99 | ALOX5 (0.49) | ALOX5RXRARXRBMRGPRX4 | |
| SCHEMBL8965251 | 0.83 | ALOX5 (0.60) | ALOX5HDAC6 | |
| SCHEMBL8965411 | 0.79 | ALOX5 (0.47) | ALOX5HDAC6 | |
| SCHEMBL8965347 | 0.79 | ALOX5 (0.48) | ALOX5HDAC6 | |
| SCHEMBL8965414 | 0.72 | ALOX5 (0.52) | ALOX5RXRARXRB | |
| SCHEMBL8965350 | 0.71 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL8801742 | 0.71 | ALOX5 (0.53) | ALOX5HDAC6 | |
| SCHEMBL16621263 | 0.70 | NR4A2 (0.53) | ALOX5RXRARXRB | |
| SCHEMBL8799338 | 0.66 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8799899 | 0.65 | ALOX5 (0.64) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |