Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966334 | 0.86 | SLC6A2 (0.39) | SLC6A2SLC6A3HTR2ASLC6A4HRH1 | |
| SCHEMBL8966352 | 0.76 | CYP3A4 (0.39) | SLC6A2LMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11604805 | 0.73 | LMNA (0.42) | SLC6A2SLC6A3HTR2ASLC6A4HRH1 | |
| SCHEMBL3906444 | 0.72 | LMNA (0.47) | SLC6A4MEN1KMT2ALMNACYP2A6 | |
| SCHEMBL2550429 | 0.70 | LMNA (0.44) | SLC6A2SLC6A3HTR2ASLC6A4HRH1 | |
| SCHEMBL11600371 | 0.70 | LMNA (0.38) | SLC6A2SLC6A3HTR2ASLC6A4HRH1 | |
| SCHEMBL8966376 | 0.69 | LMNA (0.42) | SLC6A4LMNACYP2A6MIFIDO1 | |
| SCHEMBL8965957 | 0.69 | LMNA (0.42) | SLC6A4LMNACYP2A6MIFIDO1 | |
| SCHEMBL2884978 | 0.68 | HTR2A (0.39) | SLC6A2SLC6A3HTR2ASLC6A4HRH1 | |
| SCHEMBL8966038 | 0.68 | LMNA (0.36) | SLC6A2SLC6A3HTR2ASLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490445-B1 | Catalyst compositions | SHELL INT RESEARCH (NL) | 1996-02-28 | — | — | EP | disclosed |
| US-5292700-A | Polymerization catalyst | SHELL OIL COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5218084-A | POLYMERIZATION OF CARBON MONOXIDE/PROPYLENE WITH AROMATIC AMINE | SHELL OIL COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0490445-A2 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-17 | — | — | EP | disclosed |