Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709681 | 0.76 | CYP3A4 (0.39) | TAAR1KDM4E | |
| SCHEMBL9661671 | 0.74 | CYP3A4 (0.38) | KDM4E | |
| SCHEMBL11604805 | 0.73 | LMNA (0.42) | LMNACYP2A6IDO1SLC6A2SLC6A3 | |
| SCHEMBL3906444 | 0.72 | LMNA (0.47) | LMNACYP2A6IDO1TAAR1SLC6A4 | |
| SCHEMBL11600371 | 0.70 | LMNA (0.38) | LMNACYP2A6IDO1SLC6A2SLC6A3 | |
| SCHEMBL8966376 | 0.69 | LMNA (0.42) | LMNACYP2A6IDO1TAAR1SLC6A4 | |
| SCHEMBL8965957 | 0.69 | LMNA (0.42) | LMNACYP2A6IDO1TAAR1SLC6A4 | |
| SCHEMBL8966334 | 0.68 | SLC6A2 (0.39) | LMNACYP2A6IDO1SLC6A2SLC6A3 | |
| SCHEMBL8965573 | 0.68 | SLC6A2 (0.39) | LMNACYP2A6IDO1SLC6A2SLC6A3 | |
| SCHEMBL9579902 | 0.67 | SMN1; SMN2 (0.40) | LMNACYP2A6KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490445-B1 | Catalyst compositions | SHELL INT RESEARCH (NL) | 1996-02-28 | — | — | EP | disclosed |
| EP-0490445-A2 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-17 | — | — | EP | disclosed |