Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 12/20 | 0.56 |
| ▸ | MEP1A | Q16819 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407864 | 0.87 | MEP1B (0.65) | MEP1BMEP1ABCHELTA4HFOLH1 | |
| SCHEMBL10468744 | 0.84 | BCHE (0.65) | BCHEACHEAPP | |
| SCHEMBL1456846 | 0.80 | MEP1B (0.60) | MEP1BMEP1ABCHEFOLH1 | |
| SCHEMBL14376730 | 0.80 | BCHE (0.72) | BCHEACHEAPP | |
| SCHEMBL14376142 | 0.79 | BCHE (0.74) | BCHEACHEAPP | |
| SCHEMBL14376731 | 0.79 | BCHE (0.74) | BCHEACHEAPP | |
| SCHEMBL14376859 | 0.79 | BCHE (0.74) | BCHEACHEAPP | |
| SCHEMBL40108 | 0.78 | MEP1B (0.51) | MEP1BMEP1ABCHEACHELTA4H | |
| SCHEMBL5321633 | 0.77 | L3MBTL1 (0.62) | BCHEACHEAPP | |
| SCHEMBL4405810 | 0.76 | MEP1B (0.72) | MEP1BMEP1AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | claimed |
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | claimed |