Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057946 | 0.81 | LMNA (0.42) | THRBTDP1MEN1LMNABLM | |
| SCHEMBL26361934 | 0.81 | CA12 (0.44) | ERN1THRBTDP1MEN1LMNA | |
| SCHEMBL30605883 | 0.81 | CA12 (0.44) | ERN1THRBTDP1MEN1LMNA | |
| SCHEMBL3633752 | 0.77 | POLB (0.47) | TRIM24TRIM33ERN1DAOTHRB | |
| SCHEMBL8965390 | 0.77 | ERN1 (0.47) | ERN1MEN1LMNAKMT2APOLB | |
| SCHEMBL3181540 | 0.74 | POLB (0.55) | THRBTDP1MEN1LMNABLM | |
| Phenylacetaldehyde SCHEMBL1656594 | 0.74 | TRIM24 (0.69) | TRIM24TRIM33ERN1THRBTDP1 | |
| Diphenylmethane SCHEMBL28072548 | 0.73 | TRIM24 (0.75) | TRIM24TRIM33ERN1THRBTDP1 | |
| Salicyladehyde SCHEMBL29118303 | 0.73 | TRIM24 (0.67) | TRIM24TRIM33ERN1THRBTDP1 | |
| SCHEMBL1579174 | 0.72 | ALDH1A1 (0.43) | MEN1LMNAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530136-B1 | Nematicidal agents | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| US-5451595-A | Benzoisothiazole ethers | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0530136-A2 | Nematicidal agents | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |