Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965587 | 0.84 | TSHR (0.50) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL1960823 | 0.84 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL19150998 | 0.82 | TSHR (0.37) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL8502400 | 0.81 | TSHR (0.39) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL28073212 | 0.80 | TSHR (0.60) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL27639268 | 0.79 | TSHR (0.50) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL18545341 | 0.79 | THRB (0.43) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10067025 | 0.79 | TSHR (0.44) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL4590512 | 0.78 | TSHR (0.40) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL1592258 | 0.78 | ALDH1A1 (0.41) | THRBTSHRHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547762-A | THERMOSETTING RESIN LAYER | BRIDGESTONE CORPORATION (JP) | 1996-08-20 | — | — | US | disclosed |