Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259791 | 1.00 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL1455133 | 0.79 | TDP1 (0.58) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL2350755 | 0.77 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL27337982 | 0.77 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL25664541 | 0.77 | RAB9A (0.47) | ALDH1A1HSD17B10CYP3A4LMNAATM | |
| SCHEMBL9320058 | 0.76 | TDP1 (0.54) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL18416407 | 0.76 | TDP1 (0.54) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL19992867 | 0.76 | TDP1 (0.54) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL31263135 | 0.74 | TDP1 (0.47) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL21637581 | 0.73 | TDP1 (0.64) | TDP1ALDH1A1TSHRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591290-A | The back-end production process of synthesis of quinoline and derivative thereof | SHIPENG XIA (CN) | 2009-12-02 | — | — | CN | disclosed |
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |