Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18416407 | 1.00 | TDP1 (0.54) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL20213681 | 0.92 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL20213682 | 0.92 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL13966434 | 0.86 | TDP1 (0.48) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL1455133 | 0.82 | TDP1 (0.58) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL18421307 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL18416410 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL9820447 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL23057902 | 0.78 | TDP1 (0.48) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL28296933 | 0.77 | TDP1 (0.46) | TDP1ALDH1A1TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052244-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2018-03-22 | — | — | WO | disclosed |