Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HLCS | P50747 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402138 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL9402128 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL9326015 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL28138730 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL10446067 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL10407687 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL9136883 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL194066 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL18165385 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1PKM | |
| SCHEMBL17830363 | 0.94 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419422-B1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA SAS (FR) | 2014-10-15 | — | — | EP | claimed |
| US-8624037-B2 | Imidazolidine-2,4-dione derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2014-01-07 | — | — | US | claimed |
| US-20120095068-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2012-04-19 | — | — | US | claimed |
| EP-1778827-A1 | STABLE NONAQUEOUS BLEACHING DETERGENT COMPOSITION DISPERSION | JohnsonDiversey, Inc., Renee J. Rymarz (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006014223-A1 | STABLE NONAQUEOUS BLEACHING DETERGENT COMPOSITION DISPERSION | JOHNSONDIVERSEY, INC. (US) | 2006-02-09 | — | — | WO | claimed |
| CN-1454042-A | Method for producing printing circuit board | SHEPLEY CO (US) | 2003-11-05 | — | — | CN | claimed |
| EP-0474112-B1 | Process for preparing 5-arylhydantoin | KANEGAFUCHI CHEMICAL IND (JP) | 1999-03-17 | — | — | EP | claimed |
| CN-1039283-C | Use of Porphyrins | FMC CORP (US) | 1998-07-29 | — | — | CN | claimed |
| EP-0647630-B1 | Process for producing 5-arylhydantoins | SHOWA DENKO KK (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0763073-A4 | — | — | 1997-04-16 | — | — | EP | claimed |
| US-5606071-A | Process for preparing 5-arylhydantoins using 5-hydantoin, a halogenating agent and p-phenol | SHOWA DENKO K.K. (JP) | 1997-02-25 | — | — | US | claimed |
| WO-1995027008-A1 | WET STRENGTH RESIN COMPOSITION AND METHODS OF MAKING THE SAME | HENKEL CORPORATION (US) | 1995-10-12 | — | — | WO | claimed |
| US-5436256-A | Process for the preparation of arylhydantoins | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1995-07-25 | — | — | US | claimed |
| US-5407808-A | Treating tumor with inhibitor of protoporphyrinogen conversion to heme | FMC CORPORATION (US) | 1995-04-18 | — | — | US | claimed |
| EP-0647630-A1 | Process for producing 5-arylhydantoins | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-04-12 | — | — | EP | claimed |
| US-5298502-A | Exposure to light in presence of oxidase inhibitor | FMC CORPORATION (US) | 1994-03-29 | — | — | US | claimed |
| EP-0447491-B1 | PROTOPORPHYRINOGEN INHIBITORS AND THEIR USE IN COMPOSITIONS FOR DETECTING AND TREATING TUMOURS | FMC CORP (US) | 1993-08-11 | — | — | EP | claimed |
| US-5126459-A | PROCESS FOR PREPARING 5-ARYLHYDANTOIN | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-06-30 | — | — | US | claimed |
| EP-0474112-A1 | Process for preparing 5-arylhydantoin | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-03-11 | — | — | EP | claimed |
| US-4211840-A | USING ENZYME SPECIFIC FOR D-ISOMER OF 5-SUBSTITUTED HYDANTOIN | AJINOMOTO COMPANY, INCORPORATED (JP) | 1980-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095068-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | MKI67, CCNI, CCNA1 | ALDH1A1 558/4885MAPT 4586/4885KDM4E 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.