SCHEMBL194066

SCHEMBL194066

CCCCC1NC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 1/20 0.36
GAA P10253 1/20 0.36
ADAMTS5 Q9UNA0 4/20 0.35
ADAMTS4 O75173 2/20 0.35
ADAM10 O14672 1/20 0.35
MMP12 P39900 1/20 0.35
ADAM17 P78536 1/20 0.35
ADAM9 Q13443 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17830363 1.00 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL18165385 1.00 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL896587 0.94 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL10446067 0.92 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL9402128 0.92 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL9402138 0.92 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL9326015 0.92 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL9136883 0.92 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL10407687 0.92 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1PKM
SCHEMBL15014722 0.87 SMN1; SMN2 (0.50) ALDH1A1MAPTKDM4EMEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118374903-B Cool inductor-based polyester fiber fabric, preparation method and application thereof in underwear 汕头市至上科技有限公司 2024-08-20 CN claimed
CN-115449861-A Manufacturing method of flexible titanium metal part capable of being rolled 东莞奕创表面处理科技有限公司 2022-12-09 CN claimed
US-20150056667-A1 MUTANTS OF HYDANTOINASE EVONIK OPERATIONS GMBH (DE) 2015-02-26 US claimed
US-5707837-A Method of producing (R)-tertiary leucine DEGUSSA AKTIENGESELLSCHAFT (DE) 1998-01-13 US claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed
US-3937755-A POLYESTERS HAVING IMPROVED DISPERSE DYEABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-02-10 US claimed
JP-7222593-A None JP disclosed
JP-58074645-A None JP disclosed
US-20250120400-A1 SYNTHESIS OF GLUFOSINATE USING A HYDANTOINASE-BASED PROCESS BASF SE (DE) 2025-04-17 US disclosed
US-20250034605-A1 ENZYMATIC DECARBAMOYLATION OF GLUFOSINATE DERIVATIVES BASF SE (DE) 2025-01-30 US disclosed
EP-4444732-A1 SYNTHESIS OF GLUFOSINATE USING A HYDANTOINASE-BASED PROCESS BASF SE (DE) 2024-10-16 EP disclosed
EP-4444731-A1 ENZYMATIC DECARBAMOYLATION OF GLUFOSINATE DERIVATIVES BASF SE (DE) 2024-10-16 EP disclosed
CN-118374903-B Cool inductor-based polyester fiber fabric, preparation method and application thereof in underwear 汕头市至上科技有限公司 2024-08-20 CN disclosed
WO-1993013077-A1 ANGIOTENSIN II RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1993-07-08 WO disclosed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO disclosed
EP-0160618-B1 HYDANTOIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1991-08-14 EP disclosed
US-4560752-A Phosphinates or phosphonates useful for control of weeds ZOECON CORPORATION (US) 1985-12-24 US disclosed
US-4406689-A Certain aralkyloxy or thio-pyridyl-imidazo-pyridines and their herbicidal use ZOECON CORPORATION (US) 1983-09-27 US disclosed
JP-S5874645-A PREPARATION OF DL-NORLEUCINE DAI ICHI PURE CHEM CO LTD 1983-05-06 JP disclosed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034605-A1 ENZYMATIC DECARBAMOYLATION OF GLUFOSINATE DERIVATIVES GLUL, ASNS, NAALAD2 ALDH1A1 2500/4885MAPT 2315/4885KDM4E 469/4885
US-20250120400-A1 SYNTHESIS OF GLUFOSINATE USING A HYDANTOINASE-BASED PROCESS GLUL, ASNS, DNPEP ALDH1A1 2562/4885MAPT 3721/4885KDM4E 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.