Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966168 | 0.90 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8966180 | 0.89 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL262028 | 0.86 | ALDH1A1 (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL20344268 | 0.85 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28323101 | 0.85 | TSHR (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18132825 | 0.85 | ALDH1A1 (0.55) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18495622 | 0.85 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL23062838 | 0.84 | THRB (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL25121369 | 0.83 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL25121372 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547762-A | THERMOSETTING RESIN LAYER | BRIDGESTONE CORPORATION (JP) | 1996-08-20 | — | — | US | disclosed |