SCHEMBL8966058

SCHEMBL8966058

C=CC(=O)NC(CC)(CC)CCCC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
THRA P10827 2/20 0.36
THRB P10828 2/20 0.36
TSHR P16473 5/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
FAAH O00519 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27561622 0.95 ZDHHC20 (0.49) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL8766095 0.92 ZDHHC20 (0.48) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL8765522 0.89 ALDH1A1 (0.41) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL11909202 0.86 ZDHHC20 (0.43) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL8766001 0.84 ALDH1A1 (0.42) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL28005175 0.83 ALDH1A1 (0.40) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL8764497 0.80 ZDHHC20 (0.44) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL15577127 0.80 ZDHHC20 (0.49) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL28445748 0.80 ZDHHC20 (0.49) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9
SCHEMBL8765940 0.79 MEN1 (0.50) ZDHHC20ZDHHC2ALDH1A1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5275811-A Terpolymer resin of vinyl ester, acrylamide and maleate ISP INVESTMENTS INC. (US) 1994-01-04 US disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
US-5196495-A Hair spray; terpolymer of a vinyl ester, alkyl maleate half ester and a substituted acrylamide ISP INVESTMENTS INC. (US) 1993-03-23 US disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
WO-1992013014-A1 HAIR FIXATIVE POLYMERS ISP INVESTMENTS INC. (US) 1992-08-06 WO disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed