Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 9/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966675 | 1.00 | SPHK1 (0.40) | SPHK1ALDH1A1LMNAHTTHTR2A | |
| SCHEMBL8966456 | 0.86 | SPHK2 (0.39) | SPHK1HTR2ASPHK2 | |
| SCHEMBL31323926 | 0.85 | ALDH1A1 (0.36) | ALDH1A1LMNAHTT | |
| SCHEMBL8967053 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNA | |
| SCHEMBL29135509 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAHTT | |
| SCHEMBL24274929 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHTT | |
| SCHEMBL31323999 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAHTT | |
| SCHEMBL29135546 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAHTT | |
| SCHEMBL23178806 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAHTT | |
| SCHEMBL23178746 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432661-B1 | 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same | YASHIMA KAGAKU KOGYO KK (JP) | 1996-03-06 | — | — | EP | disclosed |
| US-5141948-A | 2-SUBSTITUTED PHENYL-2-OXAZOLINE OR THIAZOLINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND INSECTICIDES AND ACARICIDES CONTAINING THE SAME | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0432661-A2 | 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |