SCHEMBL8967053

SCHEMBL8967053

CCCCCCCCCCOc1ccc(C2COC(c3c(F)cccc3F)=N2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NR5A1 Q13285 1/20 0.39
FAAH O00519 6/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
LTA4H P09960 1/20 0.38
PLA2G4B P0C869 1/20 0.38
RORC P51449 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8891468 0.85 TAAR1 (0.45)
SCHEMBL8966675 0.84 SPHK1 (0.40) ALDH1A1LMNA
SCHEMBL8892895 0.81 TAAR1 (0.48)
SCHEMBL8893924 0.78 MEN1 (0.42) ALDH1A1LMNASMN1; SMN2
SCHEMBL6980670 0.77 NPC1 (0.66) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL8693966 0.75 ALOX5 (0.42) ALDH1A1MAPTLMNANPC1RAB9A
SCHEMBL6978639 0.75 RAB9A (0.42) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL7091836 0.75 ALDH1A1 (0.38) ALDH1A1MAPTLMNANPC1RAB9A
SCHEMBL9417511 0.74 GRM2 (0.39) ALDH1A1
SCHEMBL8695558 0.74 MAPT (0.42) ALDH1A1MAPTLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3232867-A None JP disclosed
EP-0432661-B1 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same YASHIMA KAGAKU KOGYO KK (JP) 1996-03-06 EP disclosed
US-5141948-A 2-SUBSTITUTED PHENYL-2-OXAZOLINE OR THIAZOLINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND INSECTICIDES AND ACARICIDES CONTAINING THE SAME YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) 1992-08-25 US disclosed
JP-H03232867-A 2-SUBSTITUTED PHENYL-2-OXAZOLINE OR THIAZOLINE DERIVATIVE, ITS PRODUCTION, INSECTICIDE AND ACARICIDE COMPRISING SAME DERIVATIVE YASHIMA CHEM IND CO LTD 1991-10-16 JP disclosed
CN-1054422-A Derivative, its preparation method of 2-substituted-phenyl-2-thiazoline or 2-substituted benzene-2-thiazoline and contain the sterilant and the miticide of this compounds YASHIMA CHEMICAL IND INCORP (JP) 1991-09-11 CN disclosed
EP-0432661-A2 2-Substituted phenyl-2-oxazoline or thiazoline derivatives, process for producing the same and insecticides and acaricides containing the same YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) 1991-06-19 EP disclosed