Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297382 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL22202388 | 0.82 | MEN1 (0.49) | ALDH1A1HSD17B10HPGDTDP1CYP1A2 | |
| SCHEMBL6315102 | 0.82 | CYP2A6 (0.38) | ALDH1A1TSHRHSD17B10HPRT1CYP2A6 | |
| SCHEMBL19590681 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL11235332 | 0.76 | TLR8 (0.38) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL7453593 | 0.73 | GABBR2 (0.41) | ALDH1A1TSHRHSD17B10HPGDTDP1 | |
| SCHEMBL30220315 | 0.72 | TLR8 (0.41) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL959197 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL22710196 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL29484445 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375503-B1 | Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups | ELF AQUITAINE (FR) | 1996-02-28 | — | — | EP | claimed |