SCHEMBL8966490

SCHEMBL8966490

C=CC(=O)N(C(=C)CSSCCN)C(=O)C=C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
THPO P40225 1/20 0.34
MAPT P10636 2/20 0.33
EHMT2 Q96KQ7 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14673755 0.76 TSHR (0.34) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL107282 0.73 TSHR (0.39) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL21590125 0.71 TSHR (0.55) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL31707345 0.71 TSHR (0.50) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL26133478 0.71 TSHR (0.50) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL1700588 0.71 TSHR (0.55) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL28324594 0.69 TSHR (0.48) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL28091242 0.69 MAPT (0.52) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL29625321 0.65
SCHEMBL5458497 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456405-A High-strength tear-resistant conductive hydrogel suitable for friction nanogenerator and preparation and application thereof 中国科学院宁波材料技术与工程研究所 2022-05-10 CN disclosed
US-5589104-A Electrophoresis separation gel and a method for preparing an electrophoresis separation gel BAMBECK GREGORY S (US) 1996-12-31 US disclosed