Cystamine

Cystamine

SCHEMBL21590125

C=CC(N)=O.NCCSSCCN

nearest known ligand 0.55

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
ALDH1A1 P00352 1/20 0.55
FGFR4 P22455 1/20 0.55
THPO P40225 1/20 0.50
MAPT P10636 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
EHMT2 Q96KQ7 1/20 0.48
CYP1A2 P05177 1/20 0.33
NOS1 P29475 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 2/20 0.32
CYP3A4 P08684 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cystamine SCHEMBL1700588 1.00 TSHR (0.55) TSHRALDH1A1FGFR4THPOMAPT
Cystamine SCHEMBL26133478 0.85 TSHR (0.50) TSHRALDH1A1FGFR4THPOMAPT
Cystamine SCHEMBL31707345 0.85 TSHR (0.50) TSHRALDH1A1FGFR4THPOMAPT
Cystamine SCHEMBL28091242 0.83 MAPT (0.52) TSHRALDH1A1FGFR4THPOMAPT
Cystamine SCHEMBL28324594 0.83 TSHR (0.48) TSHRALDH1A1FGFR4THPOMAPT
Acrylamide SCHEMBL514219 0.81 ALDH1A1 (0.73) TSHRALDH1A1FGFR4THPOTDP1
Acrylamide SCHEMBL6005592 0.81
Acrylamide SCHEMBL17685705 0.81 ALDH1A1 (0.73) TSHRALDH1A1FGFR4THPOTDP1
Cystamine SCHEMBL445194 0.78 TSHR (0.62) TSHRALDH1A1THPOMAPTTDP1
Cystamine SCHEMBL31646100 0.78 TSHR (0.62) TSHRALDH1A1THPOMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112424242-B Degradable microsphere and application thereof 清华大学 2022-09-02 CN claimed
US-20210255074-A1 Degradable Microsphere and Use Thereof TSINGHUA UNIVERSITY (CN) 2021-08-19 US claimed
EP-3808786-A1 DEGRADABLE MICROSPHERE AND USE THEREOF Tsinghua University (CN) 2021-04-21 EP claimed
CN-112424242-A Degradable microspheres and application thereof 清华大学 2021-02-26 CN claimed
WO-2019237952-A1 DEGRADABLE MICROSPHERE AND USE THEREOF 清华大学 2019-12-19 WO claimed
CN-114891153-B All-solid-state ion conductive elastomer and preparation method and application thereof 中国科学院大学 2023-12-15 CN disclosed
CN-114644765-B Composite ion hydrogel composition and preparation method and application thereof 中国科学院上海硅酸盐研究所 2023-12-08 CN disclosed
CN-113082054-B Stem cell transfected gene delivery vector and preparation method and application thereof 中国药科大学 2023-09-26 CN disclosed
CN-116555392-A Method for fixing sequencing microsphere on inner surface of gene sequencing chip 赛纳生物科技(北京)有限公司 2023-08-08 CN disclosed
CN-116555408-A Reusable sequencing method 赛纳生物科技(北京)有限公司 2023-08-08 CN disclosed
CN-116531318-A Preparation and application of pH/redox-responsive nanogel with chemotherapy/photothermal therapy/chemodynamic therapy 首都医科大学 2023-08-04 CN disclosed
CN-113304700-B Method for preparing magnetic polymer microsphere and application thereof 上海科技大学 2023-06-02 CN disclosed
CN-116179668-A Targeting reaction complexes and their use in targeted multiplex assays 复旦大学 2023-05-30 CN disclosed
CN-112424242-B Degradable microsphere and application thereof 清华大学 2022-09-02 CN disclosed
US-20210255074-A1 Degradable Microsphere and Use Thereof TSINGHUA UNIVERSITY (CN) 2021-08-19 US disclosed
EP-3808786-A1 DEGRADABLE MICROSPHERE AND USE THEREOF Tsinghua University (CN) 2021-04-21 EP disclosed
CN-112424242-A Degradable microspheres and application thereof 清华大学 2021-02-26 CN disclosed
WO-2019237952-A1 DEGRADABLE MICROSPHERE AND USE THEREOF 清华大学 2019-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210255074-A1 Degradable Microsphere and Use Thereof STUB1, PSMD14, ACP1 TSHR 3153/4885ALDH1A1 3389/4885FGFR4 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.