SCHEMBL107282

SCHEMBL107282

C=CC(=O)N(CCSSCCN)C(=O)C=C

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
THPO P40225 1/20 0.39
MAPT P10636 2/20 0.37
EHMT2 Q96KQ7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5329184 0.81 ZDHHC20 (0.33) TSHR
SCHEMBL1092553 0.79 ALDH1A1 (0.35) TSHR
Cystamine SCHEMBL26133478 0.74 TSHR (0.50) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL31707345 0.74 TSHR (0.50) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL1700588 0.74 TSHR (0.55) TSHRTHPOMAPTEHMT2TDP1
Cystamine SCHEMBL21590125 0.74 TSHR (0.55) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL9516195 0.74 TSHR (0.43) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL8579190 0.74 TSHR (0.43) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL8966490 0.73 TSHR (0.34) TSHRTHPOMAPTEHMT2TDP1
SCHEMBL6926574 0.73 TSHR (0.34) TSHRTHPOMAPTEHMT2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121571207-A Metal in-situ anchored carbon nano-cluster catalyst and preparation method and application thereof 长江大学 2026-02-27 CN claimed
US-12534663-B2 Re-crosslinkable hyper-branched polymer gels based on a transamidation reaction THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2026-01-27 US claimed
US-20250205400-A1 ZWITTERIONIC POLYMER COATING WITH SURFACE GRAFT CROSSLINKING, PREPARATION METHOD AND APPLICATION THEREOF TIANJIN UNIVERSITY (CN) 2025-06-26 US claimed
CN-116688247-B Janus zwitterionic hydrogel anti-adhesion film and preparation method and application thereof 天津大学 2025-05-30 CN claimed
CN-120000847-A Preparation method of injectable polymeric biopolymer material for bone repair 深港产学研基地(北京大学香港科技大学深圳研修院) 2025-05-16 CN claimed
CN-119818456-A Preparation method of negatively charged melittin nanocapsules targeting tumor microenvironment 北京化工大学 2025-04-15 CN claimed
CN-115462853-B Precisely patterned selective adhesive tissue patch and preparation method thereof 东华大学 2025-04-11 CN claimed
EP-4532711-A1 METHODS AND HYDROGEL COMPOSITIONS FOR PARTITIONING BIOLOGICAL SAMPLES Bio-Rad Laboratories, Inc. (US) 2025-04-09 EP claimed
CN-119679992-A Double-layer asymmetric patch material for preventing air leakage after pulmonary surgery and preparation method and application thereof 深锐(天津)生物医学有限公司 2025-03-25 CN claimed
CN-119650834-A Gel electrolyte membrane for lithium-sulfur battery, preparation method and energy storage device 天目湖先进储能技术研究院有限公司 2025-03-18 CN claimed
US-20030113229-A1 Method for adhesion of polymers to metal-coated substrates MOTOROLA, INC. 2003-06-19 US claimed
WO-2002013956-A1 MEMBRANES AND METHOD OF MANUFACTURE THEREOF GRADIPORE LIMITED (AU) 2002-02-21 WO claimed
US-20020001821-A1 Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof MOSBACH KLAUS (SE) 2002-01-03 US claimed
US-6127154-A Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof KLAUS MOSBACH, CENTER FOR CHEMISTRY AND CHEMICAL ENGINEERING, PURE AND APPLIED BIOCHEMISTRY (SE) 2000-10-03 US claimed
EP-0489206-B1 Synthetic skin substitutes ZENITH TECHNOLOGY CORP LTD (NZ) 1997-02-19 EP claimed
US-5196190-A Polyacrylamide, polysaccharide ZENITH TECHNOLOGY CORPORATION, LIMITED (NZ) 1993-03-23 US claimed
EP-0489206-A1 Synthetic skin substitutes ZENITH TECHNOLOGY CORPORATION LIMITED (NZ) 1992-06-10 EP claimed
EP-0159694-B1 RADIATION PROCESS FOR PREPARATION OF ELECTROPHORESIS GEL MATERIAL E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-15 EP claimed
US-5069773-A Electrophoretic gel forming system OWL SCIENTIFIC, INC. 1991-12-03 US claimed
US-4626581-A CROSSLINKED ACRYLAMIDE INTERPOLYMERS BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) 1986-12-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534663-B2 Re-crosslinkable hyper-branched polymer gels based on a transamidation reaction PHOSPHO1, TERT, AS3MT TSHR 488/4885THPO 677/4885MAPT 1166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.