SCHEMBL8966529

SCHEMBL8966529

O=C(Cl)C1(C(=O)Cl)c2ccccc2CC1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.36
FABP5 Q01469 1/20 0.36
BACE1 P56817 3/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
LMNA P02545 1/20 0.35
BLM P54132 1/20 0.35
CYP2C19 P33261 2/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CHRM1 P11229 1/20 0.34
KDM1A O60341 2/20 0.33
CYP1A2 P05177 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C1 Q04828 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161565 0.87 MAPK1 (0.40) FABP7FABP5MAPTGAALMNA
SCHEMBL30376825 0.87 MAPK1 (0.40) FABP7FABP5MAPTGAALMNA
Hydrochloric Acid SCHEMBL8966532 0.85 MAPK1 (0.39) FABP7FABP5MAPTGAALMNA
SCHEMBL9405304 0.85 MAPK1 (0.39) FABP7FABP5MAPTGAALMNA
Potassium Ion SCHEMBL9405303 0.83 CYP2C19 (0.37) FABP7FABP5MAPTGAALMNA
SCHEMBL4541268 0.74 KDM1A (0.38) KDM1AMAOAMAOB
SCHEMBL9405305 0.74 CA1 (0.45) MAPTGAALMNAMAPK1ALDH1A1
SCHEMBL3148715 0.70 KDM1A (0.47) KDM1AMAOAMAOB
SCHEMBL3947348 0.70 KDM1A (0.47) CYP2C19MAPK1KDM1AMAOAMAOB
SCHEMBL2390674 0.70 KDM1A (0.41) MAPK1CHRM1KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693962-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1996-01-31 EP claimed
WO-1994023830-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'Air Liquide Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 1994-10-27 WO claimed
US-5352273-A Permeability, selectivity E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-04 US claimed
JP-2073048-A None JP disclosed
EP-0693962-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1996-01-31 EP disclosed
WO-1994023830-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'Air Liquide Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 1994-10-27 WO disclosed
US-5352273-A Permeability, selectivity E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-04 US disclosed
US-5162489-A Containing a 1,1,3-trimethylphenylindane moiety AKZO N.V. (NL) 1992-11-10 US disclosed
US-4980504-A WHICH HAVE HIGH GLASS TRANSITION TEMPERATURES AKZO N.V. (NL) 1990-12-25 US disclosed
JP-H0273048-A DIAMINE CONTAINING AROMATIC AMIDE AND POLYMER PREPARED FROM IT AKZO NV 1990-03-13 JP disclosed
EP-0357106-A1 Aromatic amide groups-containing diamines and polymers prepared therefrom AKZO N.V. (NL) 1990-03-07 EP disclosed