Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967710 | 0.98 | KMT2A (0.66) | KMT2AALDH1A1LMNADRD2MAPT | |
| SCHEMBL8966877 | 0.94 | DRD2 (0.65) | KMT2AALDH1A1LMNADRD2MEN1 | |
| SCHEMBL9296977 | 0.86 | KMT2A (0.69) | KMT2AALDH1A1LMNADRD2MAPT | |
| SCHEMBL11542164 | 0.83 | DRD2 (0.64) | KMT2ADRD2MEN1DRD3 | |
| SCHEMBL11744954 | 0.83 | KMT2A (0.81) | KMT2AALDH1A1LMNADRD2MAPT | |
| SCHEMBL13562203 | 0.82 | KMT2A (1.00) | KMT2AALDH1A1LMNADRD2MAPT | |
| SCHEMBL11740905 | 0.82 | KMT2A (1.00) | KMT2AALDH1A1LMNADRD2MAPT | |
| SCHEMBL8966878 | 0.82 | DRD2 (0.62) | KMT2AALDH1A1DRD2MEN1SLC6A3 | |
| SCHEMBL11866431 | 0.81 | KMT2A (0.78) | KMT2AALDH1A1LMNADRD2MAPT | |
| SCHEMBL11824249 | 0.81 | KMT2A (0.78) | KMT2AALDH1A1LMNADRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |
| EP-0580644-B1 | 1,3,4-TRISUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE | BASF AG (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0580644-A1 | 1,3,4-TRISUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE. | BASF AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| WO-1992018480-A1 | 1,3,4-TRISUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |