Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966947 | 0.98 | KMT2A (0.69) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| SCHEMBL8966877 | 0.96 | DRD2 (0.65) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| SCHEMBL9296977 | 0.84 | KMT2A (0.69) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| SCHEMBL8967606 | 0.82 | DRD2 (0.57) | KMT2AALDH1A1DRD2SLC6A3MEN1 | |
| Hydrochloric Acid SCHEMBL8966871 | 0.81 | KMT2A (0.79) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| Hydrochloric Acid SCHEMBL8966875 | 0.81 | KMT2A (0.79) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| SCHEMBL11542164 | 0.81 | DRD2 (0.64) | KMT2ADRD2MEN1DRD3SIGMAR1 | |
| SCHEMBL11744954 | 0.81 | KMT2A (0.81) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| SCHEMBL13562203 | 0.80 | KMT2A (1.00) | KMT2AALDH1A1LMNADRD2SLC6A3 | |
| SCHEMBL11740905 | 0.80 | KMT2A (1.00) | KMT2AALDH1A1LMNADRD2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |