Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629252 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL11810243 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL8509674 | 0.97 | — | — | |
| SCHEMBL11792912 | 0.89 | — | — | |
| SCHEMBL5163869 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL11030766 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL13864131 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL5159311 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL4609242 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRL3MBTL1DNM1SMN1; SMN2 | |
| SCHEMBL6632361 | 0.80 | DNM1 (0.30) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468434-B1 | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis | MERRELL DOW PHARMA (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5348964-A | Anticholesterol agents or fungicides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0468434-A1 | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |