SCHEMBL8967009

SCHEMBL8967009

Bc1cccc(Cl)c1N(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
HTT P42858 3/20 0.34
LMNA P02545 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
DOT1L Q8TEK3 2/20 0.34
TSHR P16473 2/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ADRA2A P08913 2/20 0.31
ADRA2B P18089 2/20 0.31
ADRA2C P18825 2/20 0.31
HTR1A P08908 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRK1 P41145 1/20 0.31
KCNH2 Q12809 1/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16746561 0.83 CYP1A2 (0.43) CYP1A2CYP2A6HTTLMNANPC1
SCHEMBL8966971 0.77 KDM4E (0.37) CYP1A2CYP2A6LMNASMN1; SMN2TSHR
SCHEMBL8967322 0.77 CYP1A2 (0.34) CYP1A2CYP2A6LMNAALDH1A1ADRA2A
SCHEMBL8966974 0.74 MAPT (0.44) CYP1A2HTTLMNASMN1; SMN2TSHR
SCHEMBL21395985 0.74 ESR1 (0.40) CYP1A2CYP2A6HTTLMNANPC1
SCHEMBL3787606 0.74 MAPT (0.44) CYP1A2CYP2A6HTTLMNANPC1
SCHEMBL8966248 0.74 CRHR1 (0.42)
SCHEMBL16534699 0.73 KCNH2 (0.42) CYP1A2CYP2A6HTTLMNANPC1
SCHEMBL21111149 0.73 CYP1A2 (0.35) CYP1A2CYP2A6HTTLMNANPC1
SCHEMBL21027096 0.73 CYP1A2 (0.35) CYP1A2CYP2A6HTTLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed