Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967059 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL8967064 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL11741505 | 0.93 | ALDH1A1 (0.87) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL9714953 | 0.91 | ALDH1A1 (0.83) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8966871 | 0.89 | KMT2A (0.79) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8966875 | 0.89 | KMT2A (0.79) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL9710832 | 0.88 | KMT2A (0.78) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL11743879 | 0.88 | KMT2A (0.78) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL11746033 | 0.86 | KMT2A (0.78) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL9710676 | 0.85 | KMT2A (0.74) | ALDH1A1KMT2ALMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |
| EP-0294294-B1 | Amine derivatives of anthracycline antibiotics | CYTOGEN CORP (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5162512-A | Treatment of cellular disorders | CYTOGEN CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992018480-A1 | 1,3,4-TRISUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992018479-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |
| US-4950738-A | ANTICARCINOGENS | CYTOGEN CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| WO-1988009823-A1 | AMINE DERIVATIVES OF ANTHRACYCLINE ANTIBIOTICS AND ANTIBODY CONJUGATES THEREOF | CYTOGEN CORPORATION (US) | 1988-12-15 | — | — | WO | disclosed |
| EP-0294294-A2 | Amine derivatives of anthracycline antibiotics | CYTOGEN CORPORATION (US) | 1988-12-07 | — | — | EP | disclosed |