Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.55 |
| ▸ | ARRB1 | P49407 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743879 | 1.00 | KMT2A (0.78) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7002758 | 0.90 | KMT2A (0.64) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8967059 | 0.88 | ALDH1A1 (1.00) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8967060 | 0.88 | ALDH1A1 (1.00) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8967064 | 0.88 | ALDH1A1 (1.00) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11745258 | 0.88 | KMT2A (0.77) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11862748 | 0.87 | KMT2A (0.75) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11744954 | 0.86 | KMT2A (0.81) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9296977 | 0.85 | KMT2A (0.69) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL13562203 | 0.85 | KMT2A (1.00) | KMT2AALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018480-A1 | 1,3,4-TRISUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |