Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717255 | 0.79 | CYP4F2 (0.39) | MAPTCYP4F2CYP4A11PKMMMP8 | |
| SCHEMBL7921583 | 0.76 | MAPT (0.37) | MAPTCYP4F2CYP4A11PKMMMP8 | |
| SCHEMBL10704347 | 0.76 | MAPT (0.40) | MAPTCYP4F2CYP4A11PKMMMP8 | |
| SCHEMBL14105288 | 0.74 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL411532 | 0.73 | CYP4F2 (0.38) | MAPTCYP4F2CYP4A11PKMMMP8 | |
| SCHEMBL9770315 | 0.73 | MEN1 (0.39) | MAPTCYP4F2CYP4A11PKMPIN1 | |
| SCHEMBL16761029 | 0.73 | PKM (0.38) | MAPTCYP4F2CYP4A11PKMTSHR | |
| SCHEMBL18956879 | 0.73 | TP53 (0.38) | MAPTCYP4F2CYP4A11PKMTSHR | |
| SCHEMBL10468127 | 0.72 | MAPT (0.37) | MAPTCYP4F2CYP4A11PKMTSHR | |
| SCHEMBL8345959 | 0.71 | GAA (0.38) | MAPTCYP4F2CYP4A11PKMMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523430-A | Protein farnesyl transferase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-04 | — | — | US | disclosed |