Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14105287 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL411532 | 0.82 | CYP4F2 (0.38) | CYP4F2CYP4A11MAPTALDH1A1TSHR | |
| SCHEMBL10704347 | 0.80 | MAPT (0.40) | CYP4F2CYP4A11MAPTALDH1A1TSHR | |
| SCHEMBL7921583 | 0.80 | MAPT (0.37) | CYP4F2CYP4A11MAPTALDH1A1TSHR | |
| SCHEMBL8967147 | 0.79 | MAPT (0.36) | CYP4F2CYP4A11MAPTALDH1A1TSHR | |
| SCHEMBL1450701 | 0.78 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1TSHRPKM | |
| SCHEMBL5663335 | 0.78 | TSHR (0.40) | ALDH1A1TSHRLMNAHSD17B10CYP3A4 | |
| SCHEMBL14105288 | 0.78 | TSHR (0.40) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL9770315 | 0.78 | MEN1 (0.39) | CYP4F2CYP4A11MAPTALDH1A1TSHR | |
| SCHEMBL16761029 | 0.78 | PKM (0.38) | CYP4F2CYP4A11MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0690890-A1 | PHOSPHORUS-CONTAINING FLAME RETARDANTS | COURTAULDS PLC (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994021724-A1 | PHOSPHORUS-CONTAINING FLAME RETARDANTS | COURTAULDS PLC (GB) | 1994-09-29 | — | — | WO | disclosed |