SCHEMBL8967162

SCHEMBL8967162

COc1ccccc1CCC[Si](C)(C)Cl

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.53
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
AOC3 Q16853 1/20 0.47
MPO P05164 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
KCNH2 Q12809 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
HRH3 Q9Y5N1 1/20 0.45
IDO1 P14902 1/20 0.44
ABCB1 P08183 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9131260 0.95 TAAR1 (0.51) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL5490794 0.88 TAAR1 (0.55) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL14469717 0.86 TAAR1 (0.56) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL15215220 0.83 TAAR1 (0.53) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL18100910 0.83 TAAR1 (0.53) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL17438137 0.82 TAAR1 (0.34) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL7831226 0.81 TAAR1 (0.69) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL8969576 0.81 CSNK1A1 (0.48) ALDH1A1MAPT
SCHEMBL1970395 0.80 TAAR1 (0.58) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL10124396 0.80 TAAR1 (0.50) TAAR1MTNR1AMTNR1BSIGMAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644888-B1 SULPHONIUM SALTS AND PROCESS FOR PRODUCING THEM WACKER CHEMIE GMBH (DE) 1996-03-13 EP disclosed
EP-0618919-B1 IODINIUM SALTS AND METHOD OF PREPARING THEM WACKER CHEMIE GMBH (DE) 1996-02-28 EP disclosed
US-5468890-A Iodonium salts and process for the preparation thereof WACKER-CHEMIE GMBH (DE) 1995-11-21 US disclosed
US-5466845-A Contain silane groups, photoinitiators WACKER-CHEMIE GMBH (DE) 1995-11-14 US disclosed
WO-1993013110-A1 IODINIUM SALTS AND METHOD OF PREPARING THEM WACKER-CHEMIE GMBH (DE) 1993-07-08 WO disclosed