SCHEMBL8969576

SCHEMBL8969576

CCCCOc1ccccc1CCC[Si](C)(C)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1A1 P48729 1/20 0.48
CSNK1D P48730 1/20 0.48
PRKCD Q05655 1/20 0.48
PAK1 Q13153 1/20 0.48
CAMK2B Q13554 1/20 0.48
CAMK2G Q13555 1/20 0.48
CAMK2D Q13557 1/20 0.48
TAOK1 Q7L7X3 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP19A1 P11511 1/20 0.47
PPARD Q03181 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.43
LTB4R Q15722 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970363 0.84 CSNK1A1 (0.47) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL919038 0.84 CYP1A2 (0.58) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL8967162 0.81 TAAR1 (0.53) MAPTALDH1A1
SCHEMBL11345175 0.80 THRA (0.55) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL9215251 0.80 THRA (0.55) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL6669407 0.80 THRA (0.55) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL11344012 0.80 THRA (0.55) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL7999552 0.80 PPARD (0.60) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL8523169 0.79 LTB4R (0.55) CSNK1A1CSNK1DPRKCDPAK1CAMK2B
SCHEMBL73826 0.79 CYP1A2 (0.52) CSNK1A1CSNK1DPRKCDPAK1CAMK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644888-B1 SULPHONIUM SALTS AND PROCESS FOR PRODUCING THEM WACKER CHEMIE GMBH (DE) 1996-03-13 EP disclosed
US-5466845-A Contain silane groups, photoinitiators WACKER-CHEMIE GMBH (DE) 1995-11-14 US disclosed
WO-1993025559-A1 SULPHONIUM SALTS AND PROCESS FOR PRODUCING THEM WACKER-CHEMIE GMBH (DE) 1993-12-23 WO disclosed