Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.72 |
| ▸ | KDM6B | O15054 | 2/20 | 0.72 |
| ▸ | KDM5C | P41229 | 2/20 | 0.72 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.72 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.72 |
| ▸ | KDM4A | O75164 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12934615 | 0.89 | KDM5C (0.55) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL10020875 | 0.86 | KDM4E (0.57) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| Dipyridyl SCHEMBL3941503 | 0.84 | KDM4C (1.00) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL913277 | 0.84 | KDM4C (1.00) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| Dipyridyl SCHEMBL21551506 | 0.84 | KDM4C (1.00) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL29562841 | 0.84 | KDM4C (1.00) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL5670461 | 0.82 | KDM4E (0.72) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| Dipyridyl SCHEMBL3954422 | 0.82 | KDM4C (0.96) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| Dipyridyl SCHEMBL8358045 | 0.82 | KDM4C (0.96) | KDM4EKDM4CKDM6BKDM5CKDM2A | |
| SCHEMBL31085057 | 0.82 | KDM4C (0.56) | KDM4EKDM4CKDM6BKDM5CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502070-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0591785-A1 | Substituted 3,4-hetarylpyrazolines, process for their preparation and their use as pesticides | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |