Dipyridyl

Dipyridyl

SCHEMBL3941503

O=C(O)c1ccnc(-c2cc(C(=O)O)ccn2)c1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 9/20 1.00
KDM5C P41229 9/20 1.00
KDM4A O75164 8/20 1.00
KDM4E B2RXH2 6/20 1.00
KDM2A Q9Y2K7 5/20 1.00
KDM3A Q9Y4C1 5/20 1.00
KDM6B O15054 4/20 1.00
P4HA1 P13674 1/20 0.67
KDM5B Q9UGL1 9/20 0.58
KDM4B O94953 4/20 0.58
JMJD6 Q6NYC1 1/20 0.57
KDM5A P29375 5/20 0.56
PIN1 Q13526 1/20 0.54
TET3 O43151 1/20 0.53
BBOX1 O75936 1/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
ASPH Q12797 1/20 0.53
KDM4D Q6B0I6 1/20 0.53
TET2 Q6N021 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29562841 1.00 KDM4C (1.00) KDM4CKDM5CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL21551506 1.00 KDM4C (1.00) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL913277 1.00 KDM4C (1.00) KDM4CKDM5CKDM4AKDM4EKDM2A
Benzoic Acid SCHEMBL30567494 0.98 KDM4C (0.96) KDM4CKDM5CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL3954422 0.98 KDM4C (0.96) KDM4CKDM5CKDM4AKDM4EKDM2A
Dipyridyl SCHEMBL8358045 0.98 KDM4C (0.96) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL863220 0.93 KDM5C (0.87) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL10000745 0.93 KDM5C (0.87) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL29766771 0.93 KDM5C (0.87) KDM4CKDM5CKDM4AKDM4EKDM2A
SCHEMBL29668070 0.93 KDM4C (0.87) KDM4CKDM5CKDM4AKDM4EKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1892270-B1 Nanoparticles of an authentification system PREENTEC AG (CH) 2009-07-22 EP claimed
EP-2049602-A2 NANOPARTICLES OF AN AUTHENTICATION SYSTEM Preentec AG (CH) 2009-04-22 EP claimed
EP-1892270-A1 Nanoparticles of an authentification system Preentec AG (CH) 2008-02-27 EP claimed
WO-2008017180-A2 NANOPARTICLES OF AN AUTHENTICATION SYSTEM PREENTEC AG (CH) 2008-02-14 WO claimed
EP-1892270-B1 Nanoparticles of an authentification system PREENTEC AG (CH) 2009-07-22 EP disclosed
EP-2049602-A2 NANOPARTICLES OF AN AUTHENTICATION SYSTEM Preentec AG (CH) 2009-04-22 EP disclosed
US-7494820-B2 Electrochemiluminescence of rare earth metal chelates BIOVERIS CORPORATION (US) 2009-02-24 US disclosed
EP-1892270-A1 Nanoparticles of an authentification system Preentec AG (CH) 2008-02-27 EP disclosed
WO-2008017180-A2 NANOPARTICLES OF AN AUTHENTICATION SYSTEM PREENTEC AG (CH) 2008-02-14 WO disclosed
US-20020197601-A1 ELECTROCHEMILUMINESCENCE OF RARE EARTH METAL CHELATES BIOVERIS CORPORATION 2002-12-26 US disclosed
EP-0580979-B1 Method of detection by inducing electrochemiluminescence IGEN INT INC (US) 2002-12-18 EP disclosed
US-5858676-A Electrochemiluminescence of rare earth metal chelates IGEN INTERNATIONAL, INC. (US) 1999-01-12 US disclosed