Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967330 | 0.88 | CHRNB2 (0.37) | ADRA2C | |
| SCHEMBL8967875 | 0.80 | CYP1A2 (0.41) | ALDH1A1TDP1HTR3EHTR3BHTR3A | |
| SCHEMBL8967839 | 0.80 | CHRNB4 (0.50) | KDM4EALDH1A1HPGDALOX12TDP1 | |
| SCHEMBL251052 | 0.77 | CHRNB2 (0.33) | ADRA2C | |
| SCHEMBL12090379 | 0.71 | CHRNB2 (0.62) | — | |
| SCHEMBL12090214 | 0.70 | CHRNA7 (0.56) | — | |
| SCHEMBL4470636 | 0.70 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2DRD2SIGMAR1 | |
| SCHEMBL31494195 | 0.69 | MEN1 (0.59) | ADRA2CGID4MAOAKDM1AMAOB | |
| SCHEMBL6181098 | 0.69 | MEN1 (0.59) | ADRA2CGID4MAOAKDM1AMAOB | |
| SCHEMBL164122 | 0.69 | MEN1 (0.59) | ADRA2CGID4MAOAKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489688-B1 | Coupling agent | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| EP-0489688-A1 | Coupling agent | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |