Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410383 | 0.89 | CYP1A2 (0.39) | CYP1A2CYP2C19MAPTLMNATDP1 | |
| SCHEMBL8967330 | 0.87 | CHRNB2 (0.37) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8967839 | 0.82 | CHRNB4 (0.50) | CHRNA7CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL8967309 | 0.80 | ADRA2C (0.52) | ALDH1A1TDP1HTR3EHTR3BHTR3A | |
| SCHEMBL251052 | 0.79 | CHRNB2 (0.33) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL6579617 | 0.71 | SIGMAR1 (0.44) | — | |
| SCHEMBL7072099 | 0.71 | CHRNB2 (0.44) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL27585153 | 0.70 | CHRNB2 (0.53) | CYP1A2CYP2C19CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL2606079 | 0.69 | CHRNB2 (0.67) | CHRNA7CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL14235482 | 0.69 | CHRNB2 (0.67) | CHRNA7CHRNB2CHRNA4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489688-B1 | Coupling agent | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| EP-0489688-A1 | Coupling agent | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |