Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967438 | 0.75 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL2079050 | 0.75 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL3296351 | 0.73 | TDP1 (0.41) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL10769654 | 0.70 | TDP1 (0.38) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL4274258 | 0.69 | TSHR (0.47) | TDP1CYP1A2CYP2A6ALDH1A1ACHE | |
| SCHEMBL11528198 | 0.69 | SMN1; SMN2 (0.37) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL60541 | 0.66 | — | — | |
| SCHEMBL29365203 | 0.66 | — | — | |
| SCHEMBL19744496 | 0.66 | TDP1 (0.55) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL1135726 | 0.66 | TDP1 (0.55) | TDP1TP53CYP1A2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514034-B1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0514034-A1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5120520-A | In presence of metal or metal-contianing catalyst | DOW CORNING CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |