Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967363 | 0.79 | TRPA1 (0.42) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL1557214 | 0.77 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL3150402 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29776872 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL1049034 | 0.74 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL8967622 | 0.72 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL7421898 | 0.72 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL271788 | 0.72 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL4269749 | 0.72 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL144808 | 0.72 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110835354-B | Process for preparing alkyl phenyl fluorosilane | 张家港市国泰华荣化工新材料有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |
| US-6414173-B1 | TRANSMETALLATION REACTION, COMPRISING: CONTACTING PALLADIUM CATALYST WITH AROYL, ALKANOYL, OR ARALKANOYL ESTER OF ALLYLIC ALCOHOL; AND HYPERVALENT SILICON SPECIES | UNIVERSITY OF MARYLAND | 2002-07-02 | — | — | US | disclosed |
| EP-0514034-B1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0514034-A1 | Silane products from reaction of solid silicon monoxide with aromatic halides | DOW CORNING CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5120520-A | In presence of metal or metal-contianing catalyst | DOW CORNING CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4874638-A | PRECOATING AN ALKALINE CARBONATE SURFACE WITH AN APROTIC SOLVENT SOLUTION CONTAINING AN ORGANO SILICON FLUORIDE; DESOLVENTIZING | WACKER-CHEMIE GMBH (DE) | 1989-10-17 | — | — | US | disclosed |