SCHEMBL8967607

SCHEMBL8967607

O=CNNc1ccc(NC(=O)Nc2cccc(-n3nnnc3S)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.39
ALDH1A1 P00352 3/20 0.36
LMNA P02545 3/20 0.36
RAB9A P51151 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35
KCNJ6 P48051 1/20 0.35
KCNJ5 P48544 1/20 0.35
KCNJ3 P48549 1/20 0.35
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
MAPK13 O15264 1/20 0.35
MAPK12 P53778 1/20 0.35
MAPK11 Q15759 1/20 0.35
MAPK14 Q16539 1/20 0.35
PTK2 Q05397 1/20 0.35
CNR2 P34972 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8650519 0.89 IDH1 (0.40) ALDH1A1LMNAL3MBTL1MAPTMAPK1
SCHEMBL14498648 0.86 TSHR (0.46) CNR1LMNARAB9AMAPTTSHR
SCHEMBL8967579 0.86 MEN1 (0.45) ALDH1A1LMNAL3MBTL1NPC1SMN1; SMN2
SCHEMBL14498666 0.84 CNR1 (0.56) CNR1ALDH1A1RAB9AMAPTMAPK14
SCHEMBL13297731 0.81 ALDH1A1 (0.40) CNR1ALDH1A1LMNARAB9AL3MBTL1
SCHEMBL14498663 0.81 SMN1; SMN2 (0.51) ALDH1A1LMNARAB9AL3MBTL1MAPT
SCHEMBL1336437 0.80 ALDH1A1 (0.41) ALDH1A1LMNARAB9AL3MBTL1CRHBP
SCHEMBL13297727 0.80 ALDH1A1 (0.44) CNR1ALDH1A1LMNARAB9AL3MBTL1
SCHEMBL14498670 0.79 GAA (0.41) CNR1ALDH1A1LMNARAB9AL3MBTL1
SCHEMBL8172135 0.79 ALDH1A1 (0.43) ALDH1A1LMNARAB9AL3MBTL1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393477-B1 Direct positive photosensitive material FUJI PHOTO FILM CO LTD (JP) 1996-07-03 EP disclosed
EP-0398355-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-03-06 EP disclosed
EP-0358170-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-08-24 EP disclosed
EP-0322702-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
US-5145765-A Containing a compound capable of releasing a development inhibitor by oxidation and a hydrazide compound FUJI PHOTO FILM CO., LTD. (JP) 1992-09-08 US disclosed
US-5104784-A Containing organic thiosulfurous and inorganic sulfurous acid derivatives; storage stable sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1992-04-14 US disclosed
US-5081009-A Non-prefogged grains FUJI PHOTO FILM CO., LTD. (JP) 1992-01-14 US disclosed
US-5061594-A PHOTOGRAPHIC NEGATIVES OR DIRECT POSITIVES FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US disclosed
US-H972-H Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
US-5028510-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-02 US disclosed
EP-0360289-A2 Positive working silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-28 EP disclosed
EP-0358170-A2 Direct positive photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-03-14 EP disclosed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP disclosed
US-4880727-A SILVER HALIDE EMULSIONS, COLLOIDS, MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1989-11-14 US disclosed
EP-0327066-A2 Direct positive photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0322702-A2 Direct positive photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0311110-A2 Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-04-12 EP disclosed
EP-0303301-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-02-15 EP disclosed
EP-0285010-A2 Method for forming a direct positive color image FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP disclosed
EP-0267482-A2 Direct positive color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP disclosed