SCHEMBL8967579

SCHEMBL8967579

O=CNNc1ccc(NC(=O)c2cccc(-n3nnnc3S)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
EPHX2 P34913 1/20 0.43
F10 P00742 3/20 0.42
PRSS1 P07477 3/20 0.42
F2 P00734 2/20 0.42
PRSS2 P07478 2/20 0.42
PRSS3 P35030 2/20 0.42
KDM4E B2RXH2 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 2/20 0.39
CTDSP1 Q9GZU7 2/20 0.39
POLB P06746 2/20 0.39
TP53 P04637 2/20 0.38
JAK2 O60674 1/20 0.38
JAK1 P23458 1/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8967607 0.86 CNR1 (0.39) MEN1KMT2AF10PRSS1ALDH1A1
SCHEMBL10680373 0.79 MEN1 (0.48) MEN1KMT2AEPHX2KDM4EUSP2
SCHEMBL5669641 0.78 POLB (0.54) MEN1KMT2AKDM4EPOLBTP53
SCHEMBL13297855 0.78 HDAC8 (0.45) MEN1KMT2AKDM4EPOLBTP53
SCHEMBL5829255 0.77 KCNK3 (0.58) MEN1KMT2APOLBTP53NPC1
SCHEMBL13297724 0.77 AOC2 (0.54) MEN1KMT2AF10PRSS1F2
SCHEMBL5829189 0.77 RAB9A (0.51) MEN1KMT2AEPHX2KDM4EPOLB
SCHEMBL8943869 0.77 TP53 (0.46) MEN1KMT2AEPHX2KDM4EUSP2
SCHEMBL19072257 0.77 EPHX2 (0.40) MEN1KMT2AEPHX2F10PRSS1
SCHEMBL8988112 0.77 PMM2 (0.35) MEN1KMT2AKDM4EPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399460-B1 Silver halide photograpic material FUJI PHOTO FILM CO LTD (JP) 1996-10-23 EP disclosed
EP-0393477-B1 Direct positive photosensitive material FUJI PHOTO FILM CO LTD (JP) 1996-07-03 EP disclosed
EP-0398355-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-03-06 EP disclosed
EP-0355818-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-05-10 EP disclosed
EP-0358170-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-08-24 EP disclosed
EP-0322702-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
US-5145765-A Containing a compound capable of releasing a development inhibitor by oxidation and a hydrazide compound FUJI PHOTO FILM CO., LTD. (JP) 1992-09-08 US disclosed
US-5081009-A Non-prefogged grains FUJI PHOTO FILM CO., LTD. (JP) 1992-01-14 US disclosed
US-5061594-A PHOTOGRAPHIC NEGATIVES OR DIRECT POSITIVES FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US disclosed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP disclosed
US-4880727-A SILVER HALIDE EMULSIONS, COLLOIDS, MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1989-11-14 US disclosed
EP-0327066-A2 Direct positive photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0322702-A2 Direct positive photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0311110-A2 Direct positive color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-04-12 EP disclosed
EP-0303301-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-02-15 EP disclosed
EP-0285010-A2 Method for forming a direct positive color image FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0267482-A2 Direct positive color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP disclosed
US-4724199-A RELEASING A FOGGING AGENT IN REDOX SYSTEM FUJI PHOTO FILM CO., LTD. (JP) 1988-02-09 US disclosed